Bacteria

What are bacteria?

Bacteria (singular: bacterium) are single-celled organisms which can only be seen through a microscope. They come in different shapes and sizes, and their sizes are measured in micrometer – which is a millionth part of a meter. There are several different types of bacteria, and they are found everywhere and in all types of environment.

There are various groups of bacteria, which belong to the same family and have evolved from the same bacteria (ancestoral). However, each of these types possess their own peculiar characteristics – which have evolved after separation from the original species. The classification of bacteria is based on many factors like morphology, DNA sequencing, requirement of oxygen and carbon-dioxide, staining methods, presence of flagellae, cell structure, etc. This article will give you the classification of these micro-organisms based on all these factors, as well as a few other factors.

The famous notion that bacterial cells in the human body outnumber human cells by a factor of 10:1 has been debunked. There are approximately 39 trillion bacterial cells in the human microbiota as personified by a “reference” 70 kg male 170 cm tall, whereas there are 30 trillion human cells in the body. This means that although they do have the upper hand in actual numbers, it is only by 30%, and not 900%

Types Of Bacteria

Bacteria are microscopic single-celled organisms that are all around us. They come in many different sizes and shapes, and this is a common way to classify them—by their morphology, or shape and appearance. The three basic shapes of bacteria are spherical, rod shaped and spiral. Spiral-shaped bacteria can be further categorized depending in part on how much spiraling they show. Not all bacteria are capable of causing disease, but each morphology-based group has at least some disease-causing representatives.

Cocci are round, spherical bacteria. They may be single bacteria or they may occur in pairs, chains or clusters of bacteria, depending on the bacterium and environmental conditions. Cocci cause many different common illnesses. Among the more common cocci are Staphylococcus aureus, which appears as a cluster of cocci. Staph aureus often grows harmlessly in the nose and on the skin, but given a chance, this organism can cause boils, pneumonia, meningitis and even toxic shock syndrome—a rare, life-threatening condition. Streptococcus pyogenes occurs as a chain of cocci and causes diseases that originate in the throat or skin, including strep throat and a related condition known as scarlet fever. Neisseria meningitidis occurs in pairs of cocci. This bacterium is an important cause of bacterial meningitis—a potentially life threatening infection, with inflammation of the brain and spinal cord.

Bacilli are rod-shaped bacteria that look like little sausages, occurring singly or in linked chains. Escherichia coli is a rod-shaped bacterium that normally lives in your intestinal tract without causing disease, however it can cause disease at other sites, such as the urinary tract. Some strains of E. coli are spread by eating or drinking contaminated food or water, causing diarrhea and potentially more widespread illness in some individuals. Corynebacterium diphtheriae, another rod-shaped bacterium, infects the respiratory tract and causes diphtheria, a vaccine-preventable disease. Bacillus anthracis is the cause of anthrax. This rod-shaped bacterium grows in long chains, can infect you through broken skin, ingestion or inhalation and is therefore considered among the organisms that have bioterrorism potential

Members of the vibrio group represent one of the three types of bacteria that have a spiral shape. Vibrio bacteria are comma-shaped, appearing like curved rods. They typically live in aquatic environments and move in a darting motion using a single flagellum, a whip-like structure. Vibrio cholerae causes cholera—an intestinal infection that causes severe diarrhea and dehydration. Drinking water contaminated by feces transmits cholera, and epidemics may occur after natural disasters and in developing countries due to poor sanitation. Cholera is a very serious disease that can lead to death if not treated promptly.

Spirilla are another subgroup of bacteria with a more rigid, corkscrew-like spiral shape. One such bacterium is Campylobacter jejuni, a cause of foodborne illness and diarrhea. Campylobacter jejuni is typically acquired in places where sanitation is poor or by eating raw or undercooked poultry. Campylobacter is among the most common causes of diarrheal illness in the United States. Helicobacter pylori is also corkscrew-shaped bacteria, and it thrives in the stomach, where it burrows into the lining. Helicobacter pylori may be living in a person’s stomach without causing symptoms, but this organism is also associated with stomach inflammation and ulcers in many people.

Spirochetes are long, thin and flexible corkscrew-shaped bacteria. They typically move in a distinctive rotating manner that allows them to be mobile in mucus-lined tissue or viscous environments. Two well-known spirochetes that cause disease in humans are Treponema pallidum and Borrelia burgdorferi. Treponema pallidum causes the sexually transmitted disease syphilis. Infection typically begins as a single sore at the site of infection. Additional lesions or rashes can develop elsewhere on the body if left untreated. Borrelia burgdorferi is transmitted through the bite of an infected deer tick and causes Lyme disease. Infection with Borrelia burgdorferi may, but does not always, result in a typical “bull’s-eye” rash. If left untreated, it can affect your heart and nervous system and cause arthritis.

Bacterial diseases

Bacteria cause disease by secreting or excreting toxins (as in botulism), by producing toxins internally, which are released when the bacteria disintegrate (as in typhoid), or by inducing sensitivity to their antigenic properties (as in tuberculosis). Other serious bacterial diseases include cholera, diphtheria, bacterial meningitis, tetanus, Lyme disease, gonorrhea, and syphilis.

1. Pulmonary Tuberculosis:

Pathogen – Mycobacterium tuberculae

Epidemiology –  Airborne & Droplet infection

Incubation Period – 2-10 weeks

Symptoms – Coughing; chest pain and bloody sputum with tuberculin.

Prophylaxis – BCG vaccine Isolation, Health education.

Therapy – Streptomycin, para-amino salicylic acid, rifampicin etc.

2. Diphtheria:

Pathogen – Corynebacterium diphtheriae

Epidemiology – Airborne & Droplet infection

Incubation Period – 2-6 days

Symptoms – Inflammation of mucosa of nasal chamber, throat etc. respiratory tract blocked.

Prophylaxis – DPT vaccine.

Therapy – Diphtheria antitoxins, Penicillin, Erythromycin.

3. Cholera:

Pathogen – Vibrio cholerae

Epidemiology – Direct & oral (with contaminated food & water)

Incubation Period – 6 hours to 2 – 3 days

Symptoms – Acute diarrhoea & dehydration.

Prophylaxis – Sanitation, boiling of water & cholera vaccine.

Therapy – Oral rehydration therapy & tetracycline.

4. Leprosy (Hansen’s Disease):

Pathogen – Mycobacterium leprae

Epidemiology – Slowest infectious & contagious

Incubation Period – 2-5 years

Symptoms – Skin hypopigmentation, nodulated skin, deformity of fingers & toes. Lepromin in skin tests.

Prophylaxis – Isolation.

Therapy – Dapsone, rifampicin, Clofazimine.

5. Pertussis (Whooping Cough):

Pathogen – Bordetella pertussis

Epidemiology – Contagious & Droplet infection

Incubation Period – 7-14 days

Symptoms – Whoops during inspiration.

Prophylaxis – DPT vaccine.

Therapy – Erythromycin.

6. Plague:

Pasteurella (or Yersinia) pestis

Epidemiology – Indirect & inoculative (vector is rat flea)

Incubation Period – 2-6 days

Symptoms – Bubonic plague affects lymph nodes; Pneumonic plague affects lungs and Septicemic plague causes anaemia.

Prophylaxis – Killing of rats & ratfleas, Plague- vaccine.

Therapy – Tetracycline, streptomycin, Chloromycetin

X